Drug resistance is one of the main hurdles for the successful treatment of Flavorings breast cancer.The synchronous targeting of apoptosis resistance and survival signal transduction pathways may be a promising approach to overcome drug resistance.In this study, we determined that evodiamine (EVO), a major constituent of the Chinese herbal medicine
Severe acute pancreatitis: clinical findings and therapeutic tools in Internal Medicine practice
BACKGROUND Recent advances in pathophysiology and therapeutic measures suggest that patients suffering from acute pancreatitis (AP) should undergo an early evaluation and treatment in Internal Medicine wards.Severe AP, usually associated with pancreatic necrosis and peripancreatic fluid collections, may be frequently complicated by distant organ(s)
Spasmodic dysphonia: description of the disease and associated neurologic disorders
Introduction: Spasmodic dysphonia (SD) is a problem that affects speech and vocalization, one of the most devastating disorders of oral communication.It is characterized by vocal quality tensaestrangulada, harshly and / or interspersed with abrupt vocal attack and a great tension in the vocal tract.The etiology of spasmodic dysphonia is unclear.Som
Abundance and Compositions of B-Vitamin-Producing Microbes in the Mammalian Gut Vary Based on Feeding Strategies
ABSTRACT Mammals maintain close associations with gut microbes that provide numerous nutritional benefits, including vitamin synthesis.While most mammals obtain sufficient vitamins from their diets, deficiencies in various B vitamins (biotin, cobalamin, riboflavin, thiamine, etc.) are reported in captive animals.Biomedical and agricultural research
From leaf to whole-plant water use efficiency (WUE) in complex canopies: Limitations of leaf WUE as a selection target
Plant water use efficiency (WUE) is becoming a key issue in semiarid areas, where crop production relies on the use of large volumes of water.Improving WUE is necessary for securing environmental sustainability of food production in these areas.Given that climate change predictions include increases in temperature and drought in semiarid regions, i